Analytical Data
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基因名
IgD
- Application
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别名
IgD；
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0DOX3
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表达区间
1-512aa
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氨基酸序列
RLQLQESGPGLVKPSETLSLTCIVSGGPIRRTGYYWGWIRQPPGKGLEWIGGVYYTGSIYYNPSLRGRVTISVDTSRNQFSLNLRSMSAADTAMYYCARGNPPPYYDIGTGSDDGIDVWGQGTTVHVSSAPTKAPDVFPIISGCRHPKDNSPVVLACLITGYHPTSVTVTWYMGTQSQPQRTFPEIQRRDSYYMTSSQLSTPLQQWRQGEYKCVVQHTASKSKKEIFRWPESPKAQASSVPTAQPQAEGSLAKATTAPATTRNTGRGGEEKKKEKEKEEQEERETKTPECPSHTQPLGVYLLTPAVQDLWLRDKATFTCFVVGSDLKDAHLTWEVAGKVPTGGVEEGLLERHSNGSQSQHSRLTLPRSLWNAGTSVTCTLNHPSLPPQRLMALREPAAQAPVKLSLNLLASSDPPEAASWLLCEVSGFSPPNILLMWLEDQREVNTSGFAPARPPPQPGSTTFWAWSVLRVPAPPSPQPATYTCVVSHEDSRTLLNASRSLEVSYVTDHGPM
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分子量
56.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Immunoglobulin D (IgD) is a class of antibodies that plays a crucial role in the immune system, mainly as an antigen receptor on B cells. Despite its significance, IgD remains one of the least understood antibody isotypes. Research into IgD recombinant protein has gained momentum to elucidate its structure, function, and role in immune responses. Unlike other immunoglobulins, IgD is found in lower concentrations in serum, and its exact functions are not fully defined; however, it is known to be involved in the activation and regulation of B cell activities. The recombinant production of IgD proteins allows for detailed studies of their binding affinities and interactions with antigens. Recent advances in recombinant DNA technology enable the expression of IgD in various systems, which has facilitated the investigation of its role in health and disease, including allergies and autoimmune disorders. Moreover, understanding the molecular mechanisms of IgD could lead to novel therapeutic approaches for modulating immune responses, enhancing vaccine efficacy, or treating immunological diseases. The ongoing research into IgD recombinant proteins not only helps to uncover the mysteries surrounding this antibody isotype but also opens new avenues for the development of innovative immunotherapies.
