Analytical Data
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基因名
GRIA3
- Application
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别名
GRIA3；GluA3；GLUR3；GLURC；Glutamate receptor 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P42263
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表达区间
151-250aa
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氨基酸序列
SLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL
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分子量
14.0kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GRIA3, a member of the glutamate receptor family, plays a critical role in synaptic transmission and plasticity within the central nervous system, particularly in mediating excitatory neurotransmission. Its involvement in various neurophysiological processes makes it a significant target for understanding neurological disorders, including epilepsy, schizophrenia, and neurodegenerative diseases. Research has shown that alterations in GRIA3 expression or function can contribute to the pathological mechanisms underlying these conditions. Recombinant GRIA3 protein studies are essential for elucidating its specific functional properties, interactions with other proteins, and regulatory mechanisms. By producing and characterizing recombinant GRIA3, researchers can dissect its role in synaptic function and signal transduction pathways. Additionally, this research facilitates the development of potential therapeutic strategies aimed at modulating GRIA3 activity, which could lead to novel treatments for related neurological disorders. Thus, the study of GRIA3 recombinant protein is not only fundamental for basic neuroscience but also holds promise for advancing our understanding of various brain disorders and developing targeted pharmacological interventions.
