Analytical Data
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基因名
TXNRD2
- Application
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别名
TXNRD2；KIAA1652；TRXR2；Thioredoxin reductase 2. mitochondrial
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NNW7
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表达区间
37-524aa
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氨基酸序列
QRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCSG
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分子量
68.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TXNRD2 (Thioredoxin Reductase 2) is a crucial enzyme that plays a significant role in cellular redox homeostasis and the regulation of oxidative stress. This protein is part of the thioredoxin system, which is instrumental in maintaining the balance between reduced and oxidized states within cells, thereby influencing various biological processes such as cell proliferation, apoptosis, and signaling pathways. Research into TXNRD2 has gained prominence due to its implications in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. Dysregulation of TXNRD2 has been linked to increased oxidative stress, contributing to cellular damage and pathogenesis. The understanding of TXNRD2's structure, function, and regulation can pave the way for novel therapeutic strategies aimed at modulating its activity. Recombinant TXNRD2 protein is thus a valuable tool for studying its biochemical properties, mechanisms of action, and interactions with other cellular components. Researchers utilize recombinant techniques to produce this protein in order to investigate its functions in deeper detail, paving the path for potential applications in drug development and disease management. Overall, the study of TXNRD2 not only enhances our understanding of redox biology but also holds promise for advancing therapeutic interventions for related health conditions.
